Neuroscience
Bauer PM, Hanson JL, Pierson RK, Davidson RJ, & Pollak SD. (2009). Cerebellar Volume and Cognitive Functioning in Children Who Experienced Early Deprivation. Biological Psychiatry. 2009 Aug 4. [Epub ahead of print]
University of Wisconsin-Madison, Madison, Wisconsin.
BACKGROUND: The cerebellum is a brain region recognized primarily in the coordination of movement and related accessory motor functions. In addition, emerging evidence implicates the cerebellum in cognitive processes and suggests that this brain region might be subject to experience-dependent changes in structure. Therefore, the aim of this study was to evaluate the role of early environmental deprivation in the maturation of the cerebellum and aspects of cognitive development. METHODS: Structural magnetic resonance imaging volumes of 12 cerebellar sub-regions from 31 previously neglected and 30 typically developing children were compared with subjects' corresponding neuropsychological test scores. RESULTS: Neglected children had smaller volume of the superior-posterior cerebellar lobes. Moreover, superior-posterior lobe volume was found to mediate neuropsychological test performance differences between groups, with larger volumes yielding better outcomes on tests of memory and planning. CONCLUSIONS: These data support the importance of experience-dependent changes in cerebellar structure and highlight the role of the cerebellum in higher cognitive functions.
PMID: 19660739 [PubMed - as supplied by publisher
- Neuropsychology Abstract Of The Day: Developmental Neuropsychology
Brain development of very preterm and very low-birthweight children in childhood and adolescence: A meta-analysis Developmental Medicine and Child Neurology. 2012 Jan 28; de Kieviet JF, Zoetebier L, van Elburg RM, Vermeulen RJ, Oosterlaan J Abstract Aim ...
- Neuropsychology Abstract Of The Day: Perinatal Cortical Growth And Its Cognitive Correlates
Perinatal cortical growth and childhood neurocognitive abilities Neurology. 2011 Oct 12; Rathbone R, Counsell SJ, Kapellou O, Dyet L, Kennea N, Hajnal J, Allsop JM, Cowan F, Edwards AD Abstract OBJECTIVE:This observational cohort study addressed the hypothesis...
- Neuropsychology Abstract Of The Day: Fmri Study Of Digit Symbol Task
Usui N, Haji T, Maruyama M, Katsuyama N, Uchida S, Hozawa A, Omori K, Tsuji I, Kawashima R, & Taira M. (2009). Cortical areas related to performance of WAIS Digit Symbol Test: a functional imaging study. Neurosci Lett. Jul 21. Many neuropsychological...
- Neuropsychology Abstract Of The Day: Neurodegeneration In Alzheimer Disease
de Jong LW, van der Hiele K, Veer IM, Houwing JJ, Westendorp RG, Bollen EL, de Bruin PW, Middelkoop HA, van Buchem MA, & van der Grond J. Strongly reduced volumes of putamen and thalamus in Alzheimer's disease: An MRI study. Brain. 2008 Nov 20. Department...
- Abstract Of The Day: Neuropsychology Of Mild Cognitive Impairment (mci)
Lopez OL, Becker JT, Jagust W, Fitzpatrick A, Carlson M, T DU, Breitner J, Lyketsos C, Jones B, Kawas C, & Kuller LH. Neuropsychological characteristics of mild cognitive impairment subgroups. Journal of Neurology Neurosurgery and Psychiatry. 2005 Aug...
Neuroscience
Neuropsychology Abstract of the Day: Developmental Deprivation and the Cerebellum
Bauer PM, Hanson JL, Pierson RK, Davidson RJ, & Pollak SD. (2009). Cerebellar Volume and Cognitive Functioning in Children Who Experienced Early Deprivation. Biological Psychiatry. 2009 Aug 4. [Epub ahead of print]
University of Wisconsin-Madison, Madison, Wisconsin.
BACKGROUND: The cerebellum is a brain region recognized primarily in the coordination of movement and related accessory motor functions. In addition, emerging evidence implicates the cerebellum in cognitive processes and suggests that this brain region might be subject to experience-dependent changes in structure. Therefore, the aim of this study was to evaluate the role of early environmental deprivation in the maturation of the cerebellum and aspects of cognitive development. METHODS: Structural magnetic resonance imaging volumes of 12 cerebellar sub-regions from 31 previously neglected and 30 typically developing children were compared with subjects' corresponding neuropsychological test scores. RESULTS: Neglected children had smaller volume of the superior-posterior cerebellar lobes. Moreover, superior-posterior lobe volume was found to mediate neuropsychological test performance differences between groups, with larger volumes yielding better outcomes on tests of memory and planning. CONCLUSIONS: These data support the importance of experience-dependent changes in cerebellar structure and highlight the role of the cerebellum in higher cognitive functions.
PMID: 19660739 [PubMed - as supplied by publisher
- Neuropsychology Abstract Of The Day: Developmental Neuropsychology
Brain development of very preterm and very low-birthweight children in childhood and adolescence: A meta-analysis Developmental Medicine and Child Neurology. 2012 Jan 28; de Kieviet JF, Zoetebier L, van Elburg RM, Vermeulen RJ, Oosterlaan J Abstract Aim ...
- Neuropsychology Abstract Of The Day: Perinatal Cortical Growth And Its Cognitive Correlates
Perinatal cortical growth and childhood neurocognitive abilities Neurology. 2011 Oct 12; Rathbone R, Counsell SJ, Kapellou O, Dyet L, Kennea N, Hajnal J, Allsop JM, Cowan F, Edwards AD Abstract OBJECTIVE:This observational cohort study addressed the hypothesis...
- Neuropsychology Abstract Of The Day: Fmri Study Of Digit Symbol Task
Usui N, Haji T, Maruyama M, Katsuyama N, Uchida S, Hozawa A, Omori K, Tsuji I, Kawashima R, & Taira M. (2009). Cortical areas related to performance of WAIS Digit Symbol Test: a functional imaging study. Neurosci Lett. Jul 21. Many neuropsychological...
- Neuropsychology Abstract Of The Day: Neurodegeneration In Alzheimer Disease
de Jong LW, van der Hiele K, Veer IM, Houwing JJ, Westendorp RG, Bollen EL, de Bruin PW, Middelkoop HA, van Buchem MA, & van der Grond J. Strongly reduced volumes of putamen and thalamus in Alzheimer's disease: An MRI study. Brain. 2008 Nov 20. Department...
- Abstract Of The Day: Neuropsychology Of Mild Cognitive Impairment (mci)
Lopez OL, Becker JT, Jagust W, Fitzpatrick A, Carlson M, T DU, Breitner J, Lyketsos C, Jones B, Kawas C, & Kuller LH. Neuropsychological characteristics of mild cognitive impairment subgroups. Journal of Neurology Neurosurgery and Psychiatry. 2005 Aug...