Neuroscience
Antiviral therapy against cytomegalovirus (CMV) -- typically only thought of as a threat in immunosuppressed patients -- was linked to dramatically improved survival in patients with glioblastoma, based on one center's experience.
Donald M. O'Rourke, MD, associate professor of Neurosurgery, agreed that the findings were striking. However, it's too soon to try the strategy in the clinic, he cautioned, citing the retrospective single-center design and possible selection bias. Infection with this member of the Epstein-Barr family is endemic, so findings over the years that it was present in glioblastomas and other tumor types were long dismissed as not causal, Dr. O'Rourke explained.
"There should be a level of excitement with this result," he told MedPage Today. "Not only is it intriguing but it would dovetail nicely into some contemporary approaches we're already doing."
Read the full MedPageToday article.
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- Dr. Brem Talks About High Recurrence Rate For Glioblastoma
Steven Brem, MDSteven Brem, MD, professor of Neurosurgery and director of Neurosurgical Oncology, is quoted in a Philly.com story detailing the outlook for patients who, like former Phillies catcher Darren Daulton, are diagnosed with the brain cancer...
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Neuroscience
Antiviral May Boost Survival in Brain Cancer
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| Donald M. O'Rourke, MD |
Donald M. O'Rourke, MD, associate professor of Neurosurgery, agreed that the findings were striking. However, it's too soon to try the strategy in the clinic, he cautioned, citing the retrospective single-center design and possible selection bias. Infection with this member of the Epstein-Barr family is endemic, so findings over the years that it was present in glioblastomas and other tumor types were long dismissed as not causal, Dr. O'Rourke explained.
"There should be a level of excitement with this result," he told MedPage Today. "Not only is it intriguing but it would dovetail nicely into some contemporary approaches we're already doing."
Read the full MedPageToday article.
Penn Neurosurgery provides comprehensive surgical management of disorders of the brain, spinal cord and peripheral nervous system.
Learn more about Penn Neurosurgery.
Learn more about Penn Neurosurgery.
- Personalized T Cell Therapy Shows Promise In Stopping Brain Tumor Growth
A recent study, published in Science Translational Medicine, suggests hope for glioblastoma patients. The approach, which included members from the Perelman School of Medicine at the University of Pennsylvania and the Novartis Institutes for BioMedical...
- Five Surgeons From Penn Neurosurgery Earn 'top Doc' Honors
Each year, Philadelphia magazine recognizes the area’s outstanding doctors in their Top Doctors issue. The list is viewed as a “gold standard for those seeking the finest medical care in the Philadelphia area.” We are pleased to announce that five...
- Vp Biden Says Son Underwent Successful Procedure
Donald O' Rourke, MDDonald O'Rourke, MD, associate professor of Neurosurgery, speaks with CBS3 regarding Delaware Attorney General Beau Biden's continuing medical issues. While Dr. O'Rourke is not involved in Biden's case, he notes...
- Dr. Brem Talks About High Recurrence Rate For Glioblastoma
Steven Brem, MDSteven Brem, MD, professor of Neurosurgery and director of Neurosurgical Oncology, is quoted in a Philly.com story detailing the outlook for patients who, like former Phillies catcher Darren Daulton, are diagnosed with the brain cancer...
- Dr. O'rourke Discusses Aggressive Treatment Facing Darren Daulton
Donald O'Rourke, MDPenn Medicine neurosurgeon Donald O'Rourke, MD, was interviewed by Comcast SportsNet and 6ABC discussing the outlook for former Phillies player Darren Daulton, who was diagnosed with the brain cancer glioblastoma following surgery...