Neuroscience
Landscape test for assessing visual memory in Alzheimer's disease
Rev Neurol. 2011 Jul 1; 53(1): 1-7
Valls-Pedret C, Olives J, Bosch B, Caprile C, Castellví M, Molinuevo JL, Rami L
Abstract
INTRODUCTION: Visual episodic memory is affected in the early phases of Alzheimer's disease (AD).
AIMS: To design a visual memory test free of any verbal content, to offer its normative values in the elderly population in Spain, to validate the test in a group of patients with mild AD and to determine its capacity to discriminate between subjects with AD and controls.
SUBJECTS AND METHODS: The study involved a sample of 263 subjects (137 controls and 126 patients with AD) over 50 years of age. The landscape test consists of a first part in which participants are shown 25 photographs of landscapes. Five minutes later, the previous 25 photos are shown again together with 25 new pictures, and the subject must recognise the ones that have already been seen. The statistical analysis was performed using the Student t test for independent measures, ANCOVA, linear regression, Pearson's correlation and the ROC curve.
RESULTS: In the control group, sex and schooling did not have any significant effect on the results, although differences were found between the youngest group (50-59 years) and the oldest age group (equal to or above 80 years). Findings show that there is a significant difference between the mean scores on the landscape test obtained by the two groups (control: 44.06 ± 3.2; AD: 34.25 ± 6.6; p < 0.001). The area under the curve from the landscape test was 0.904, with a sensitivity of 0.82 and a specificity of 0.85.
CONCLUSIONS: The landscapes test is a simple, sensitive and novel instrument for assessing visual memory in early AD.
PMID: 21678318 [PubMed - indexed for MEDLINE]
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Neuroscience
Neuropsychology Abstract of the Day: Visual Memory Assessment
Landscape test for assessing visual memory in Alzheimer's disease
Rev Neurol. 2011 Jul 1; 53(1): 1-7
Valls-Pedret C, Olives J, Bosch B, Caprile C, Castellví M, Molinuevo JL, Rami L
Abstract
INTRODUCTION: Visual episodic memory is affected in the early phases of Alzheimer's disease (AD).
AIMS: To design a visual memory test free of any verbal content, to offer its normative values in the elderly population in Spain, to validate the test in a group of patients with mild AD and to determine its capacity to discriminate between subjects with AD and controls.
SUBJECTS AND METHODS: The study involved a sample of 263 subjects (137 controls and 126 patients with AD) over 50 years of age. The landscape test consists of a first part in which participants are shown 25 photographs of landscapes. Five minutes later, the previous 25 photos are shown again together with 25 new pictures, and the subject must recognise the ones that have already been seen. The statistical analysis was performed using the Student t test for independent measures, ANCOVA, linear regression, Pearson's correlation and the ROC curve.
RESULTS: In the control group, sex and schooling did not have any significant effect on the results, although differences were found between the youngest group (50-59 years) and the oldest age group (equal to or above 80 years). Findings show that there is a significant difference between the mean scores on the landscape test obtained by the two groups (control: 44.06 ± 3.2; AD: 34.25 ± 6.6; p < 0.001). The area under the curve from the landscape test was 0.904, with a sensitivity of 0.82 and a specificity of 0.85.
CONCLUSIONS: The landscapes test is a simple, sensitive and novel instrument for assessing visual memory in early AD.
PMID: 21678318 [PubMed - indexed for MEDLINE]
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Odor identification deficits identify Parkinson's disease patients with poor cognitive performance Movement Disorders. 2011 Sep;26(11):2045-50 Damholdt MF, Borghammer P, Larsen L, Ostergaard K Abstract Olfactory dysfunction is a prodromal and prevalent...
- Computerized Cognitive Testing: A New Cogstate Paper
Reliability of repeated cognitive assessment of dementia using a brief computerized battery American Journal of Alzheimers Disease and Other Dementias. 2011 Jun; 26(4): 326-333. Hammers D, Spurgeon E, Ryan K, Persad C, Heidebrink J, Barbas N, Albin R,...
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Jiang RS, Su MC, Liang KL, Shiao JY, Wu SH, & Hsin CH. A pilot study of a traditional Chinese version of the University of Pennsylvania Smell Identification Test for application in Taiwan. American Journal of Rhinol Allergy. 2010 Jan-Feb;24(1):45-50....
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O'Sullivan M, Morris RG, & Markus HS. Brief cognitive assessment for patients with cerebral small vessel disease. Journal of Neurology, Neurosurgery, and Psychiatry. 2005 Aug; 76(8): 1140-1145. Division of Clinical Neuroscience, St George's Hospital...
- Abstract Of The Day: Neuropsychological Assessment
Garces-Redondo M, Santos S, Perez-Lazaro C, Pascual-Millan LF. The supermarket test: Preliminary normative data in our milieu (in Spanish). Rev Neurol. 2004 Sep 1-15; 39(5): 415-8. Hospital Clinico Universitario Lozano Blesa, Zaragoza, Espana. ...