Neuroscience
Reliability of repeated cognitive assessment of dementia using a brief computerized battery
American Journal of Alzheimers Disease and Other Dementias. 2011 Jun; 26(4): 326-333.
Hammers D, Spurgeon E, Ryan K, Persad C, Heidebrink J, Barbas N, Albin R, Frey K, Darby D, Giordani B
Abstract
OBJECTIVE: The aim of this study was to evaluate the short-term stability and reliability of a brief computerized cognitive battery in established dementia types.
METHOD: Patients were administered the computerized battery twice with administrations approximately 2 hours apart, with intervening conventional neuropsychological tests. Patients were classified clinically, via consensus conference, as healthy controls (n = 23), mild cognitive impairment (n = 20), Alzheimer's disease (n = 52), dementia with Lewy Bodies ([DLB], n = 10), or frontotemporal dementia (n = 9).
RESULTS: Minimal practice effects were evident across Cog-State test administrations. Small magnitude improvements were seen across all groups on a working memory task, and healthy controls showed a mild practice effect on the accuracy of associative learning.
CONCLUSIONS: In established dementia, administration of the CogState tasks appears sensitive to cognitive impairment in dementia. Repeat administration also provided acceptable stability and test-retest reliability with minimal practice effects at short test-retest intervals despite intervening cognitive challenges.
PMID: 21636581 [PubMed - indexed for MEDLINE]
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Neuroscience
Computerized Cognitive Testing: A New CogState Paper
Reliability of repeated cognitive assessment of dementia using a brief computerized battery
American Journal of Alzheimers Disease and Other Dementias. 2011 Jun; 26(4): 326-333.
Hammers D, Spurgeon E, Ryan K, Persad C, Heidebrink J, Barbas N, Albin R, Frey K, Darby D, Giordani B
Abstract
OBJECTIVE: The aim of this study was to evaluate the short-term stability and reliability of a brief computerized cognitive battery in established dementia types.
METHOD: Patients were administered the computerized battery twice with administrations approximately 2 hours apart, with intervening conventional neuropsychological tests. Patients were classified clinically, via consensus conference, as healthy controls (n = 23), mild cognitive impairment (n = 20), Alzheimer's disease (n = 52), dementia with Lewy Bodies ([DLB], n = 10), or frontotemporal dementia (n = 9).
RESULTS: Minimal practice effects were evident across Cog-State test administrations. Small magnitude improvements were seen across all groups on a working memory task, and healthy controls showed a mild practice effect on the accuracy of associative learning.
CONCLUSIONS: In established dementia, administration of the CogState tasks appears sensitive to cognitive impairment in dementia. Repeat administration also provided acceptable stability and test-retest reliability with minimal practice effects at short test-retest intervals despite intervening cognitive challenges.
PMID: 21636581 [PubMed - indexed for MEDLINE]
- Neuropsychology Abstract Of The Day: Prospective Memory
Remember to Buy Milk on the Way Home! A Meta-analytic Review of Prospective Memory in Mild Cognitive Impairment and Dementia. Journal of the International Neuropsychological Society. 2012 May 18;:1-11 Authors: van den Berg E, Kant N, Postma A Abstract...
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Relationships Between Behavioral Syndromes and Cognitive Domains in Alzheimer Disease: The Impact of Mood and Psychosis American Journal of Geriatric Psychiatry. 2011 Nov 1; Koppel J, Goldberg TE, Gordon ML, Huey E, Davies P, Keehlisen L, Huet S, Christen...
- Neuropsychology Abstract Of The Day: Amnestic Mild Cognitive Impairment (amci)
Outcome of Mild Cognitive Impairment Comparing Early Memory Profiles. American Journal of Geriatric Psychiatry. 2011 Sep 19; Authors: Gómez-Tortosa E, Mahillo-Fernández I, Guerrero R, Montoya J, Alonso A, Sainz MJ Abstract BACKGROUND:: Finding variables...
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Today's recommended read deals with an important neuropsychological assessment issue in the domain of aging and the potential to identify the presence of cognitive problems that might (emphasis on "might" - such findings in a screen are not definitive)...
- Neuropsychology Abstract Of The Day: Parkinson's Disease
Pagonabarraga J, Kulisevsky J, Llebaria G, García-Sánchez C, Pascual-Sedano B, & Gironell A. Parkinson's disease-cognitive rating scale: A new cognitive scale specific for Parkinson's disease. Movement Disorders. 2008 Mar 31 [Epub ahead of print]....