Neuroscience
Are self-reported symptoms of executive dysfunction associated with objective executive function performance following mild to moderate traumatic brain injury?
Journal of Clinical and Experimental Neuropsychology. 2011 Jul;33(6):704-14
Schiehser DM, Delis DC, Filoteo JV, Delano-Wood L, Han SD, Jak AJ, Drake AI, Bondi MW
Abstract
Background and objective: We examined the relationship between self-reported pre- and post-injury changes in executive dysfunction, apathy, disinhibition, and depression, and performance on neuropsychological tests of executive function, attention/processing speed, and memory in relation to mood levels and effort test performance in individuals in the early stages of recovery from mild to moderate traumatic brain injury (TBI). Method: Participants were 71 noncombat military personnel who were in a semiacute stage of recovery (<3 months post injury) from mild to moderate TBI. Pre- and post-TBI behaviors were assessed with the Frontal Systems Behavior Scale (FrSBe; Grace & Malloy, 2001 ) and correlated with levels of depressive symptoms, effort test performance, and performance on objective measures of attention, executive function, and memory. Results: Self-reported symptoms of executive dysfunction generally failed to predict performance on objective measures of executive function and memory, although they predicted poorer performance on measures of attention/processing speed. Instead, higher levels of depressive symptomatology best predicted poorer performance on measures of executive function and memory. However, the relationship between memory performance and TBI symptoms was no longer significant when effort performance was controlled. Conclusions: Our findings suggest that, among individuals in early recovery from mild to moderate TBI, self-reported depressive symptoms, rather than patients' cognitive complaints, are associated with objective executive function. However, self-reported cognitive complaints may be associated with objectively measured inattention and slow processing speed.
PMID: 21958432 [PubMed - in process]
- Neuropsychology Abstract Of The Day: Apathy In Traumatic Brain Injury
A Multidimensional Approach to Apathy after Traumatic Brain Injury. Neuropsycholology Review 2013 Aug 7; Arnould A, Rochat L, Azouvi P, & Van der Linden MAbstractApathy is commonly described following traumatic brain injury (TBI) and is associated with...
- Neuropsychology Abstract Of The Day: Assessment Of Social Cognition In Tbi
An active area of test development and research in contemporary clinical neuropsychology: Social Cognition Impairments in Relation to General Cognitive Deficits, Injury Severity and Prefrontal Lesions in Traumatic Brain Injury Patients. Journal of Neurotrauma....
- Neuropsychology Abstract Of The Day: Tbi Clinical Trials
Today's recommended reading addresses proposed efficacy measures for use in clinical trials related to traumatic brain injury (TBI): Bagiella E, Novack TA, Ansel B, Diaz-Arrastia R, Dikmen S, Hart T, & Temkin N. Measuring Outcome in Traumatic Brain...
- Business World: Synthetic Blood International, Inc. And Traumatic Brain Injury
From a company press release:Synthetic Blood Announces Positive Results from Traumatic Brain Injury Preclinical Study COSTA MESA, Calif.--(BUSINESS WIRE)--Oct. 24, 2005--Synthetic Blood International, Inc. (OTCBB:SYBD) today announced that...
- Abstract Of The Day: Neuropsychology Assessment & Executive Function
Busch RM, McBride A, Curtiss G, & Vanderploeg RD. The components of executive functioning in traumatic brain injury. Journal of Clinical and Experimental Neuropsychology. 2005 Nov; 27(8): 1022-1032. James A. Haley Veterans' Hospital, Tampa, Florida,...
Neuroscience
Neuropsychology Abstract of the Day: Traumatic Brain Injury
Are self-reported symptoms of executive dysfunction associated with objective executive function performance following mild to moderate traumatic brain injury?
Journal of Clinical and Experimental Neuropsychology. 2011 Jul;33(6):704-14
Schiehser DM, Delis DC, Filoteo JV, Delano-Wood L, Han SD, Jak AJ, Drake AI, Bondi MW
Abstract
Background and objective: We examined the relationship between self-reported pre- and post-injury changes in executive dysfunction, apathy, disinhibition, and depression, and performance on neuropsychological tests of executive function, attention/processing speed, and memory in relation to mood levels and effort test performance in individuals in the early stages of recovery from mild to moderate traumatic brain injury (TBI). Method: Participants were 71 noncombat military personnel who were in a semiacute stage of recovery (<3 months post injury) from mild to moderate TBI. Pre- and post-TBI behaviors were assessed with the Frontal Systems Behavior Scale (FrSBe; Grace & Malloy, 2001 ) and correlated with levels of depressive symptoms, effort test performance, and performance on objective measures of attention, executive function, and memory. Results: Self-reported symptoms of executive dysfunction generally failed to predict performance on objective measures of executive function and memory, although they predicted poorer performance on measures of attention/processing speed. Instead, higher levels of depressive symptomatology best predicted poorer performance on measures of executive function and memory. However, the relationship between memory performance and TBI symptoms was no longer significant when effort performance was controlled. Conclusions: Our findings suggest that, among individuals in early recovery from mild to moderate TBI, self-reported depressive symptoms, rather than patients' cognitive complaints, are associated with objective executive function. However, self-reported cognitive complaints may be associated with objectively measured inattention and slow processing speed.
PMID: 21958432 [PubMed - in process]
- Neuropsychology Abstract Of The Day: Apathy In Traumatic Brain Injury
A Multidimensional Approach to Apathy after Traumatic Brain Injury. Neuropsycholology Review 2013 Aug 7; Arnould A, Rochat L, Azouvi P, & Van der Linden MAbstractApathy is commonly described following traumatic brain injury (TBI) and is associated with...
- Neuropsychology Abstract Of The Day: Assessment Of Social Cognition In Tbi
An active area of test development and research in contemporary clinical neuropsychology: Social Cognition Impairments in Relation to General Cognitive Deficits, Injury Severity and Prefrontal Lesions in Traumatic Brain Injury Patients. Journal of Neurotrauma....
- Neuropsychology Abstract Of The Day: Tbi Clinical Trials
Today's recommended reading addresses proposed efficacy measures for use in clinical trials related to traumatic brain injury (TBI): Bagiella E, Novack TA, Ansel B, Diaz-Arrastia R, Dikmen S, Hart T, & Temkin N. Measuring Outcome in Traumatic Brain...
- Business World: Synthetic Blood International, Inc. And Traumatic Brain Injury
From a company press release:Synthetic Blood Announces Positive Results from Traumatic Brain Injury Preclinical Study COSTA MESA, Calif.--(BUSINESS WIRE)--Oct. 24, 2005--Synthetic Blood International, Inc. (OTCBB:SYBD) today announced that...
- Abstract Of The Day: Neuropsychology Assessment & Executive Function
Busch RM, McBride A, Curtiss G, & Vanderploeg RD. The components of executive functioning in traumatic brain injury. Journal of Clinical and Experimental Neuropsychology. 2005 Nov; 27(8): 1022-1032. James A. Haley Veterans' Hospital, Tampa, Florida,...