Neuroscience
Ackermann H, Mathiak K, & Riecker A. The contribution of the cerebellum to speech production and speech perception: Clinical and functional imaging data. Cerebellum. 2007; 6(3): 202-13.
Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen.
A classical tenet of clinical neurology proposes that cerebellar disorders may give rise to speech motor disorders (ataxic dysarthria), but spare perceptual and cognitive aspects of verbal communication. During the past two decades, however, a variety of higher-order deficits of speech production, e.g., more or less exclusive agrammatism, amnesic or transcortical motor aphasia, have been noted in patients with vascular cerebellar lesions, and transient mutism following resection of posterior fossa tumors in children may develop into similar constellations. Perfusion studies provided evidence for cerebello-cerebral diaschisis as a possible pathomechanism in these instances. Tight functional connectivity between the language-dominant frontal lobe and the contralateral cerebellar hemisphere represents a prerequisite of such long-distance effects. Recent functional imaging data point at a contribution of the right cerebellar hemisphere, concomitant with language-dominant dorsolateral and medial frontal areas, to the temporal organization of a prearticulatory verbal code ('inner speech'), in terms of the sequencing of syllable strings at a speaker's habitual speech rate. Besides motor control, this network also appears to be engaged in executive functions, e.g., subvocal rehearsal mechanisms of verbal working memory, and seems to be recruited during distinct speech perception tasks. Taken together, thus, a prearticulatory verbal code bound to reciprocal right cerebellar/left frontal interactions might represent a common platform for a variety of cerebellar engagements in cognitive functions. The distinct computational operation provided by cerebellar structures within this framework appears to be the concatenation of syllable strings into coarticulated sequences.
PMID: 17786816 [PubMed - in process]
- Stroke Cures Man Of Life-long Stammer
The cerebellum is coloured green in this modelThanks to the success of the King's Speech movie, most of us are familiar with the 'developmental' kind of stammering that begins in childhood. However, more rarely, stammering can also have a...
- I Miss You But I Haven't Met You Yet
i miss you but i haven't met you yet so special but it hasn't happened yet you are gorgeous but i haven't met you yet i remember but it hasn't happened yet -- Björk, I Miss You Remembering The Past, Envisioning The Future As Björk...
- Abstract Of The Day: Aphasia
Hengst JA, Frame SR, Neuman-Stritzel T, & Gannaway R. Using others' words: Conversational use of reported speech by individuals with aphasia and their communication partners. Journal of Speech, Language, and Hearing Research. 2005 Feb; 48(1): 137-156....
- Abstract Of The Day: Primary Progressive Aphasia (ppa)
Clark DG, Charuvastra A, Miller BL, Shapira JS, Mendez MF. Fluent versus nonfluent primary progressive aphasia: A comparison of clinical and functional neuroimaging features. Brain and Language 2005 Jul; 94(1): 54-60. David Geffen School of Medicine,...
- Abstract Of The Day: Aphasia
Saygin AP, Wilson SM, Dronkers NF, Bates E. Action comprehension in aphasia: Linguistic and non-linguistic deficits and their lesion correlates. Neuropsychologia. 2004; 42(13): 1788-804. Department of Cognitive Science, University of California,...
Neuroscience
Neuropsychology Abstract of the Day: Speech and the Cerebellum
Ackermann H, Mathiak K, & Riecker A. The contribution of the cerebellum to speech production and speech perception: Clinical and functional imaging data. Cerebellum. 2007; 6(3): 202-13.
Department of General Neurology, Hertie Institute for Clinical Brain Research, University of Tübingen.
A classical tenet of clinical neurology proposes that cerebellar disorders may give rise to speech motor disorders (ataxic dysarthria), but spare perceptual and cognitive aspects of verbal communication. During the past two decades, however, a variety of higher-order deficits of speech production, e.g., more or less exclusive agrammatism, amnesic or transcortical motor aphasia, have been noted in patients with vascular cerebellar lesions, and transient mutism following resection of posterior fossa tumors in children may develop into similar constellations. Perfusion studies provided evidence for cerebello-cerebral diaschisis as a possible pathomechanism in these instances. Tight functional connectivity between the language-dominant frontal lobe and the contralateral cerebellar hemisphere represents a prerequisite of such long-distance effects. Recent functional imaging data point at a contribution of the right cerebellar hemisphere, concomitant with language-dominant dorsolateral and medial frontal areas, to the temporal organization of a prearticulatory verbal code ('inner speech'), in terms of the sequencing of syllable strings at a speaker's habitual speech rate. Besides motor control, this network also appears to be engaged in executive functions, e.g., subvocal rehearsal mechanisms of verbal working memory, and seems to be recruited during distinct speech perception tasks. Taken together, thus, a prearticulatory verbal code bound to reciprocal right cerebellar/left frontal interactions might represent a common platform for a variety of cerebellar engagements in cognitive functions. The distinct computational operation provided by cerebellar structures within this framework appears to be the concatenation of syllable strings into coarticulated sequences.
PMID: 17786816 [PubMed - in process]
- Stroke Cures Man Of Life-long Stammer
The cerebellum is coloured green in this modelThanks to the success of the King's Speech movie, most of us are familiar with the 'developmental' kind of stammering that begins in childhood. However, more rarely, stammering can also have a...
- I Miss You But I Haven't Met You Yet
i miss you but i haven't met you yet so special but it hasn't happened yet you are gorgeous but i haven't met you yet i remember but it hasn't happened yet -- Björk, I Miss You Remembering The Past, Envisioning The Future As Björk...
- Abstract Of The Day: Aphasia
Hengst JA, Frame SR, Neuman-Stritzel T, & Gannaway R. Using others' words: Conversational use of reported speech by individuals with aphasia and their communication partners. Journal of Speech, Language, and Hearing Research. 2005 Feb; 48(1): 137-156....
- Abstract Of The Day: Primary Progressive Aphasia (ppa)
Clark DG, Charuvastra A, Miller BL, Shapira JS, Mendez MF. Fluent versus nonfluent primary progressive aphasia: A comparison of clinical and functional neuroimaging features. Brain and Language 2005 Jul; 94(1): 54-60. David Geffen School of Medicine,...
- Abstract Of The Day: Aphasia
Saygin AP, Wilson SM, Dronkers NF, Bates E. Action comprehension in aphasia: Linguistic and non-linguistic deficits and their lesion correlates. Neuropsychologia. 2004; 42(13): 1788-804. Department of Cognitive Science, University of California,...