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From the BBC, a report about a recent research study published in the journal Neuron:
[ ... Read the full article ... ]
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Anthony H. Risser | neuroscience | neuropsychology | brain
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Neuroscience
p25 and Memory Functioning
From the BBC, a report about a recent research study published in the journal Neuron:
'Jekyll and Hyde' dementia clue
BBC
10 December 2005
[snip]
In the study, the researchers "switched on" p25 at will in the brain's learning and memory centre, the hippocampus.
In these mice, they found that switching on p25 for only two weeks boosted learning and memory compared to normal mice.
But if the p25 was switched on for six weeks, mice displayed impaired learning and memory in tests.
Physiological studies showed that these mice showed significant brain damage and lost nerve cells in the hippocampus.
But those who had elevated p25 levels for just two weeks had no such effects.
The researchers concluded that short-term production of p25 boosts learning - but long term exposure affects the ability to form new memories.
The researchers, led by Dr Li-Huei Tsai, say the study suggested that the protein was normally beneficial, helping form memories and enable learning.
But if there was too much p25, perhaps because of other changes in the brain linked to dementias, nerve cells can die.
[snip]
[ ... Read the full article ... ]
-
Anthony H. Risser | neuroscience | neuropsychology | brain
- Memory: Bdnf And Micrornas
Making memories: How one protein does it The JHU Gazette 12 March 2012 [snip] "Studying tiny bits of genetic material that control protein formation in the brain, Johns Hopkins scientists say that they have new clues to how memories are made and how drugs...
- Memory
A press release rom the NIH: Genetic Tags Reveal Secrets of Memories’ Staying Power in Mice A better understanding of how memory works is emerging from a newfound ability to link a learning experience in a mouse to consequent changes in the inner workings...
- Abstract Of The Day: Malnutrition
Nakagawasai O, Yamadera F, Sato S, Taniguchi R, Hiraga H, Arai Y, Murakami H, Mawatari K, Niijima F, Tan-No K, & Tadano T. Alterations in cognitive function in prepubertal mice with protein malnutrition: relationship to changes in choline acetyltransferase....
- Retinal Cells And Melanopsin
From the BBC: Doctors Make Eye Cells See Light Scientists have found how to make eye cells sensitive to light, opening new ways to treat some forms of blindness. Experts at Imperial College London teamed up with colleagues at the University of...
- Memory Circuitry
This press release from the Howard Hughes Medical Institute discusses a newly published paper on memory formation in the brain:Brain Circuit May Permit Scientists to Eavesdrop on Memory Formation 07 Oct 2004 Howard Hughes Medical Institute...