Neuroscience
Benzion Beilin; Dan Hoofien; Ravit Poran; Inbal Gral; Galina Grinevich; Berta Butin; Eduard Mayburd; & Yehuda Shavit. Comparison of two patient-controlled analgesia techniques on neuropsychological functioning in the immediate postoperative period. Journal of Clinical and Experimental Neuropsychology, Volume 30, Issue 6, August 2008, 674-682.
Pain may contribute to cognitive decline, which is a common complication in the early postoperative period. We compared the effects of two common pain management techniques, intravenous patient-controlled analgesia (PCA-IV) and patient-controlled epidural analgesia (PCEA), on cognitive functioning in the immediate postoperative period. Patients hospitalized for elective surgery were randomly assigned to one of the treatment groups (30 patients per group). A battery of objective, standardized neuropsychological tests was administered preoperatively and 24 hours after surgery. Pain intensity was also evaluated. Nonoperated volunteers served as controls. Patients of the PCA-IV group exhibited significantly higher pain scores than did patients of the PCEA group. PCA-IV patients exhibited significant deterioration in the postoperative period in all the neuropsychological measures, while the PCEA patients exhibited significant deterioration only in one cognitive index, compared to controls.
Keywords: Cognitive function; Local anaesthetics; Opiates; PCA-IV; PCEA; Postoperative pain
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Neuroscience
Neuropsychology Abstract of the Day: Post-operative Pain, Cognition, and PCA Techniques
Benzion Beilin; Dan Hoofien; Ravit Poran; Inbal Gral; Galina Grinevich; Berta Butin; Eduard Mayburd; & Yehuda Shavit. Comparison of two patient-controlled analgesia techniques on neuropsychological functioning in the immediate postoperative period. Journal of Clinical and Experimental Neuropsychology, Volume 30, Issue 6, August 2008, 674-682.
Pain may contribute to cognitive decline, which is a common complication in the early postoperative period. We compared the effects of two common pain management techniques, intravenous patient-controlled analgesia (PCA-IV) and patient-controlled epidural analgesia (PCEA), on cognitive functioning in the immediate postoperative period. Patients hospitalized for elective surgery were randomly assigned to one of the treatment groups (30 patients per group). A battery of objective, standardized neuropsychological tests was administered preoperatively and 24 hours after surgery. Pain intensity was also evaluated. Nonoperated volunteers served as controls. Patients of the PCA-IV group exhibited significantly higher pain scores than did patients of the PCEA group. PCA-IV patients exhibited significant deterioration in the postoperative period in all the neuropsychological measures, while the PCEA patients exhibited significant deterioration only in one cognitive index, compared to controls.
Keywords: Cognitive function; Local anaesthetics; Opiates; PCA-IV; PCEA; Postoperative pain
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Falling and breaking a hip can have a devastating effect on older people’s lives. Alongside pain, depression and loss of cognitive functioning, it’s been known for some time that fear of falling is one of several factors that can impede their recovery...
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Atchison TB, Massman PJ, & Doody RS. Baseline cognitive function predicts rate of decline in basic-care abilities of individuals with dementia of the Alzheimer's type. Archives of Clinical Neuropsychology. 2006 Dec 13; [Epub ahead of print]. Department...
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von Lehe M, Lutz M, Kral T, Schramm J, Elger CE, & Clusmann H. Correlation of health-related quality of life after surgery for mesial temporal lobe epilepsy with two seizure outcome scales. Epilepsy and Behavior 2006 Aug; 9(1): 73-82. Department of Neurosurgery,...
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