Neuroscience
Haramati S, Soroker N, Dudai Y, & Levy DA. The posterior parietal cortex in recognition memory: A neuropsychological study. Neuropsychologia. 2007 Nov 29 [Epub ahead of print]
Department of Neurobiology, Weizmann Institute of Science, P.O. Box 26, Rehovot 76100, Israel.
Several recent functional neuroimaging studies have reported robust bilateral activation (L>R) in lateral posterior parietal cortex and precuneus during recognition memory retrieval tasks. It has not yet been determined what cognitive processes are represented by those activations. In order to examine whether parietal lobe-based processes are necessary for basic episodic recognition abilities, we tested a group of 17 first-incident CVA patients whose cortical damage included (but was not limited to) extensive unilateral posterior parietal lesions. These patients performed a series of tasks that yielded parietal activations in previous fMRI studies: yes/no recognition judgments on visual words and on colored object pictures and identifiable environmental sounds. We found that patients with left hemisphere lesions were not impaired compared to controls in any of the tasks. Patients with right hemisphere lesions were not significantly impaired in memory for visual words, but were impaired in recognition of object pictures and sounds. Two lesion-behavior analyses - area-based correlations and voxel-based lesion symptom mapping (VLSM) - indicate that these impairments resulted from extra-parietal damage, specifically to frontal and lateral temporal areas. These findings suggest that extensive parietal damage does not impair recognition performance. We suggest that parietal activations recorded during recognition memory tasks might reflect peri-retrieval processes, such as the storage of retrieved memoranda in a working memory buffer for further cognitive processing.
PMID: 18178228 [PubMed - as supplied by publisher]
- Neuropsychology Abstract Of The Day: Assessment Of Social Cognition In Tbi
An active area of test development and research in contemporary clinical neuropsychology: Social Cognition Impairments in Relation to General Cognitive Deficits, Injury Severity and Prefrontal Lesions in Traumatic Brain Injury Patients. Journal of Neurotrauma....
- Neuropsychology Abstract Of The Day: Fmri Study Of Digit Symbol Task
Usui N, Haji T, Maruyama M, Katsuyama N, Uchida S, Hozawa A, Omori K, Tsuji I, Kawashima R, & Taira M. (2009). Cortical areas related to performance of WAIS Digit Symbol Test: a functional imaging study. Neurosci Lett. Jul 21. Many neuropsychological...
- Neuropsychology Abstract Of The Day: Mild Cognitive Impairment (mci)
Karas G, Sluimer J, Goekoop R, van der Flier W, Rombouts S, Vrenken H, Scheltens P, Fox N, & Barkhof F. Amnestic Mild Cognitive Impairment: Structural MR Imaging Findings Predictive of Conversion to Alzheimer Disease. American Journal of Neuroradiology....
- Abstract Of The Day: Memory Distortion
Schacter DL, Slotnick SD. The cognitive neuroscience of memory distortion. Neuron. 2004 Sep 30;44(1):149-60. Department of Psychology, Harvard University, Cambridge, MA 02138 USA. Memory distortion occurs in the laboratory and in everyday life....
- Abstract Of The Day: Aphasia
Saygin AP, Wilson SM, Dronkers NF, Bates E. Action comprehension in aphasia: Linguistic and non-linguistic deficits and their lesion correlates. Neuropsychologia. 2004; 42(13): 1788-804. Department of Cognitive Science, University of California,...
Neuroscience
Neuropsychology Abstract of the Day: Parietal Function
Haramati S, Soroker N, Dudai Y, & Levy DA. The posterior parietal cortex in recognition memory: A neuropsychological study. Neuropsychologia. 2007 Nov 29 [Epub ahead of print]
Department of Neurobiology, Weizmann Institute of Science, P.O. Box 26, Rehovot 76100, Israel.
Several recent functional neuroimaging studies have reported robust bilateral activation (L>R) in lateral posterior parietal cortex and precuneus during recognition memory retrieval tasks. It has not yet been determined what cognitive processes are represented by those activations. In order to examine whether parietal lobe-based processes are necessary for basic episodic recognition abilities, we tested a group of 17 first-incident CVA patients whose cortical damage included (but was not limited to) extensive unilateral posterior parietal lesions. These patients performed a series of tasks that yielded parietal activations in previous fMRI studies: yes/no recognition judgments on visual words and on colored object pictures and identifiable environmental sounds. We found that patients with left hemisphere lesions were not impaired compared to controls in any of the tasks. Patients with right hemisphere lesions were not significantly impaired in memory for visual words, but were impaired in recognition of object pictures and sounds. Two lesion-behavior analyses - area-based correlations and voxel-based lesion symptom mapping (VLSM) - indicate that these impairments resulted from extra-parietal damage, specifically to frontal and lateral temporal areas. These findings suggest that extensive parietal damage does not impair recognition performance. We suggest that parietal activations recorded during recognition memory tasks might reflect peri-retrieval processes, such as the storage of retrieved memoranda in a working memory buffer for further cognitive processing.
PMID: 18178228 [PubMed - as supplied by publisher]
- Neuropsychology Abstract Of The Day: Assessment Of Social Cognition In Tbi
An active area of test development and research in contemporary clinical neuropsychology: Social Cognition Impairments in Relation to General Cognitive Deficits, Injury Severity and Prefrontal Lesions in Traumatic Brain Injury Patients. Journal of Neurotrauma....
- Neuropsychology Abstract Of The Day: Fmri Study Of Digit Symbol Task
Usui N, Haji T, Maruyama M, Katsuyama N, Uchida S, Hozawa A, Omori K, Tsuji I, Kawashima R, & Taira M. (2009). Cortical areas related to performance of WAIS Digit Symbol Test: a functional imaging study. Neurosci Lett. Jul 21. Many neuropsychological...
- Neuropsychology Abstract Of The Day: Mild Cognitive Impairment (mci)
Karas G, Sluimer J, Goekoop R, van der Flier W, Rombouts S, Vrenken H, Scheltens P, Fox N, & Barkhof F. Amnestic Mild Cognitive Impairment: Structural MR Imaging Findings Predictive of Conversion to Alzheimer Disease. American Journal of Neuroradiology....
- Abstract Of The Day: Memory Distortion
Schacter DL, Slotnick SD. The cognitive neuroscience of memory distortion. Neuron. 2004 Sep 30;44(1):149-60. Department of Psychology, Harvard University, Cambridge, MA 02138 USA. Memory distortion occurs in the laboratory and in everyday life....
- Abstract Of The Day: Aphasia
Saygin AP, Wilson SM, Dronkers NF, Bates E. Action comprehension in aphasia: Linguistic and non-linguistic deficits and their lesion correlates. Neuropsychologia. 2004; 42(13): 1788-804. Department of Cognitive Science, University of California,...