Neuroscience
Jensen MP, Mardekian J, Lakshminarayanan M, & Boye ME. Validity of 24-h recall ratings of pain severity: Biasing effects of "Peak" and "End" pain. Pain. 2008 Jul 15; 137(2): 422-427.
Department of Rehabilitation Medicine, Box 356490, University of Washington School of Medicine, Seattle, WA 98195-6490, USA.
Despite the frequent use of pain recall ratings in clinical research, there remains doubt about the ability of individuals to accurately recall their pain. In particular, previous research indicates the possibility that the most pain experienced during a recall period and the most recent pain experienced (known as peak and end effects, respectively) might bias recall ratings. The current study used data from a published clinical trial to determine the relative validity of a 24-h recall rating of average post-operative pain and the nature and extent of any biasing influence of peak and end effects on nine separate 24-h recall ratings. The results supported a statistically significant but small biasing influence of both peak and end pain. Also, the influence of peak pain was stronger than that of end pain. However, the biasing impact of both peak and end pain together was very small, suggesting that 24-h recall ratings are adequately valid indicants of average pain for patients participating in post-surgery clinical pain trials.
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Neuroscience
Neuropsychology Abstract of the Day: Pain Assessment
Jensen MP, Mardekian J, Lakshminarayanan M, & Boye ME. Validity of 24-h recall ratings of pain severity: Biasing effects of "Peak" and "End" pain. Pain. 2008 Jul 15; 137(2): 422-427.
Department of Rehabilitation Medicine, Box 356490, University of Washington School of Medicine, Seattle, WA 98195-6490, USA.
Despite the frequent use of pain recall ratings in clinical research, there remains doubt about the ability of individuals to accurately recall their pain. In particular, previous research indicates the possibility that the most pain experienced during a recall period and the most recent pain experienced (known as peak and end effects, respectively) might bias recall ratings. The current study used data from a published clinical trial to determine the relative validity of a 24-h recall rating of average post-operative pain and the nature and extent of any biasing influence of peak and end effects on nine separate 24-h recall ratings. The results supported a statistically significant but small biasing influence of both peak and end pain. Also, the influence of peak pain was stronger than that of end pain. However, the biasing impact of both peak and end pain together was very small, suggesting that 24-h recall ratings are adequately valid indicants of average pain for patients participating in post-surgery clinical pain trials.
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It's still too early for me to blog about aggressive measures to control severe pain in cancer patients, despite my best intentions. I don't know when/if I'll be able to write a proper post on the topic. For now, I'll just list a few references,...
- Upcoming Videocast: The Neuroimaging Of Pain (07 Nov 2011)
From a press release from the NIH: Stanford researcher to speak at NIH on the role of neuroimaging in understanding pain NCCAM presents Opening Windows to the Brain: Lessons Learned in the Neuroimaging of Pain [snippet] What: Sean Mackey, M.D., Ph.D.,...
- Pain Research
From King's College London: Innovative Partnership for Pain Research 10 Mar 2010, PR 48/10 "King’s has partnered with Pfizer to create an open innovation laboratory for pain research. As part of the partnership, a small team of Pfizer scientists...
- Neuropsychology Abstract Of The Day: Post-operative Pain, Cognition, And Pca Techniques
Benzion Beilin; Dan Hoofien; Ravit Poran; Inbal Gral; Galina Grinevich; Berta Butin; Eduard Mayburd; & Yehuda Shavit. Comparison of two patient-controlled analgesia techniques on neuropsychological functioning in the immediate postoperative period. Journal...
- Upcoming Event: American Pain Society, 8-10 May 2008, Tampa Florida
The annual meeting of the APS takes place next week in Florida. Visit the conference homepage for details: Link. From the conference homepage: Conference Purpose and Objectives "The 27th Annual Scientific Meeting of the American Pain Society will offer...