Neuroscience
Wittenberg D, Possin KL, Rascovsky K, Rankin KP, Miller BL, & Kramer JH. The Early Neuropsychological and Behavioral Characteristics of Frontotemporal Dementia. Neuropsychological Review. 2008 Feb 29 [Epub ahead of print]
Memory and Aging Center, University of California—San Francisco Medical Center, San Francisco, CA, USA.
Frontotemporal lobar degeneration (FTLD) represent a constellation of disorders that may be overlooked or misdiagnosed, despite being fairly common presenile neurodegenerative diseases. Although the cognitive disorder can be difficult to document, particularly early in the dementia course, neuropsychological evaluation can assist in the diagnosis. Neuropsychologists are in an excellent position to draw from related disciplines like personality theory and social psychology to better assess the types of changes that characterize the prodromal and early phases of the disease. This review summarizes the current state of the field in the diagnosis of FTLD and discusses the emerging role of neuropsychology in elucidating the brain organization of complex processes including empathy, behavioral control and inhibition, reward systems, appetitive behaviors, emotional regulation, and goal-orientation. As this review underscores, frontotemporal dementia remains a powerful model for studying brain-behavior relationships.
PMID: 18311522 [PubMed - as supplied by publisher]
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Neuroscience
Neuropsychology Abstract of the Day: Frontotemporal Dementia
Wittenberg D, Possin KL, Rascovsky K, Rankin KP, Miller BL, & Kramer JH. The Early Neuropsychological and Behavioral Characteristics of Frontotemporal Dementia. Neuropsychological Review. 2008 Feb 29 [Epub ahead of print]
Memory and Aging Center, University of California—San Francisco Medical Center, San Francisco, CA, USA.
Frontotemporal lobar degeneration (FTLD) represent a constellation of disorders that may be overlooked or misdiagnosed, despite being fairly common presenile neurodegenerative diseases. Although the cognitive disorder can be difficult to document, particularly early in the dementia course, neuropsychological evaluation can assist in the diagnosis. Neuropsychologists are in an excellent position to draw from related disciplines like personality theory and social psychology to better assess the types of changes that characterize the prodromal and early phases of the disease. This review summarizes the current state of the field in the diagnosis of FTLD and discusses the emerging role of neuropsychology in elucidating the brain organization of complex processes including empathy, behavioral control and inhibition, reward systems, appetitive behaviors, emotional regulation, and goal-orientation. As this review underscores, frontotemporal dementia remains a powerful model for studying brain-behavior relationships.
PMID: 18311522 [PubMed - as supplied by publisher]
- Spindle Neurons And Frontotemporal Dementia
More on spindle neurons (or von Economo neurons), the next new thing: Window into human behavior, brain disease UCSF scientists have identified a cell population that is a primary target of the degenerative brain disease known as frontotemporal dementia,...
- Regarding The Pain Of Others
That's the title of a book (2003, Farrar, Straus & Giroux) by the late Susan Sontag. ''Let the atrocious images haunt us. Even if they are only tokens, and cannot possibly encompass most of the reality to which they refer, they still...
- Neuropsychology Abstract Of The Day: Mild Cognitive Impairment (mci)
Bondi MW, Jak AJ, Delano-Wood L, Jacobson MW, Delis DC, & Salmon DP. Neuropsychological Contributions to the Early Identification of Alzheimer's Disease. Neuropsychological Review. 2008 Mar 18. A wealth of evidence demonstrates that a prodromal period...
- Abstract Of The Day: Mild Cognitive Impairment (mci) & Dementia
Hodges JR, Erzinclioglu S, & Patterson K. Evolution of Cognitive Deficits and Conversion to Dementia in Patients with Mild Cognitive Impairment: A Very-Long-Term Follow-Up Study. Dementia and Geriatric Cognitive Disorders. 2006 Apr 4; 21(5-6): 380-391...
- Abstract Of The Day: Dementia
Godbolt AK, Josephs KA, Revesz T, Warrington EK, Lantos P, King A, Fox NC, Al Sarraj S, Holton J, Cipolotti L, Khan MN, & Rossor MN. Sporadic and familial dementia with ubiquitin-positive tau-negative inclusions: Clinical features of one histopathological...