Neuroscience
Pignatti R, Rabuffetti M, Imbornone E, Mantovani F, Alberoni M, Farina E, & Canal N. Specific impairments of selective attention in mild Alzheimer's disease. Journal of Clinical and Experimental Neuropsychology. 2005 May; 27(4): 436-448.
Neurorehabilitation Unit, Universita di Milano, Fondazione Don Carlo Gnocchi IRCCS, Milan, Italy.
The aim of the present study was to evaluate selective visual attention in subjects affected by Alzheimer's Disease (AD), by means of a computerized spatial exploration test that adopts a Touch Screen (TS) interface, which has already proved able to characterize alternative strategies in performing search tasks. We assessed a group of 16 patients affected by mild to moderate AD, comparing them with 16 control subjects matched for age and education. In the experimental tasks the performance of the AD patients was worse than that of the normal elderly, both quantitatively (slower speeds) and qualitatively (poorer planning and higher number of omissions and perseverations). In the visual attention tasks there appeared to be no close connection between AD patients' performance and increased Reaction Times (RT); this evidenced a specific role of non-elementary cognitive structures enclosed in a higher attentional domain, rather than a general decrease in the speed of basic cognitive processes. Our results are in line with specific AD literature: while psychomotor speed and lower attention levels (sensorimotor) are preferentially impaired in subcortical forms of dementia, the higher levels of selective and divided attention could be the first to deteriorate and appear more markedly disrupted in the Alzheimer type of dementia.
PMID: 15962690 [PubMed - in process]
-
Anthony H. Risser
neuroscience | neuropsychology | brain | alzheimer disease
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Neuroscience
Abstract of the Day: Alzheimer Disease
Pignatti R, Rabuffetti M, Imbornone E, Mantovani F, Alberoni M, Farina E, & Canal N. Specific impairments of selective attention in mild Alzheimer's disease. Journal of Clinical and Experimental Neuropsychology. 2005 May; 27(4): 436-448.
Neurorehabilitation Unit, Universita di Milano, Fondazione Don Carlo Gnocchi IRCCS, Milan, Italy.
The aim of the present study was to evaluate selective visual attention in subjects affected by Alzheimer's Disease (AD), by means of a computerized spatial exploration test that adopts a Touch Screen (TS) interface, which has already proved able to characterize alternative strategies in performing search tasks. We assessed a group of 16 patients affected by mild to moderate AD, comparing them with 16 control subjects matched for age and education. In the experimental tasks the performance of the AD patients was worse than that of the normal elderly, both quantitatively (slower speeds) and qualitatively (poorer planning and higher number of omissions and perseverations). In the visual attention tasks there appeared to be no close connection between AD patients' performance and increased Reaction Times (RT); this evidenced a specific role of non-elementary cognitive structures enclosed in a higher attentional domain, rather than a general decrease in the speed of basic cognitive processes. Our results are in line with specific AD literature: while psychomotor speed and lower attention levels (sensorimotor) are preferentially impaired in subcortical forms of dementia, the higher levels of selective and divided attention could be the first to deteriorate and appear more markedly disrupted in the Alzheimer type of dementia.
PMID: 15962690 [PubMed - in process]
-
Anthony H. Risser
neuroscience | neuropsychology | brain | alzheimer disease
- Neuropsychology Abstract Of The Day: Alzheimer's Disease Progression
Measuring Alzheimer disease progression with transition probabilities: Estimates from NACC-UDS Curr Alzheimer Res. 2011 Nov 28; Spackman DE, Kadiyala S, Neumann PJ, Veenstra DL, Sullivan SD Abstract Objectives: Estimate the probabilities, for Alzheimer's...
- Neuropsychology Abstract Of The Day: Alzheimer's Disease
Relationships Between Behavioral Syndromes and Cognitive Domains in Alzheimer Disease: The Impact of Mood and Psychosis American Journal of Geriatric Psychiatry. 2011 Nov 1; Koppel J, Goldberg TE, Gordon ML, Huey E, Davies P, Keehlisen L, Huet S, Christen...
- Neuropsychology Abstract Of The Day: Traumatic Brain Injury
Are self-reported symptoms of executive dysfunction associated with objective executive function performance following mild to moderate traumatic brain injury? Journal of Clinical and Experimental Neuropsychology. 2011 Jul;33(6):704-14 Schiehser DM, Delis...
- Neuropsychology Abstract Of The Day: Cognitive Correlates Of Impulsive Behavior In Mlld Alzheimer's Disease
A multidimensional approach to impulsivity changes in mild Alzheimer's disease and control participants: Cognitive correlates Cortex. 2011 Sep 2; Rochat L, Billieux J, Juillerat Van der Linden AC, Annoni JM, Zekry D, Gold G, Van der Linden M Abstract...
- Fda: Alzheimer Disease, Aricept (donepezil Hydrochloride)
From the FDA last week: FDA Approves Expanded Use of Treatment for Patients With Severe Alzheimer's Disease FOR IMMEDIATE RELEASE P06-168 October 13, 2006 Media Inquiries: Susan Cruzan, 301-827-6242 Consumer Inquiries: 888-INFO-FDA...