Neuroscience
From the New York Times:
Johnson & Johnson Reports Reminyl Deaths
By THE ASSOCIATED PRESS
Published: January 21, 2005
Filed at 5:08 p.m. ET
RARITAN, N.J. (AP) -- Patients taking Alzheimer's drug Reminyl in a test for another use had higher death rates than those taking a placebo, Johnson & Johnson Pharmaceutical Research & Development LLC announced Friday.
The patients had mild cognitive impairment, and the J&J company is no longer pursuing Reminyl as a treatment for the condition and has not submitted any applications for such use, spokeswoman Carol Goodrich said.
Reminyl was approved in 2001 as a treatment for mild to moderate Alzheimer's disease. The higher death rate was not observed in Alzheimer's trials, Goodrich said.
[ ... Read the full article ...] (free registration required)
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From the FDA last week: FDA Approves Expanded Use of Treatment for Patients With Severe Alzheimer's Disease FOR IMMEDIATE RELEASE P06-168 October 13, 2006 Media Inquiries: Susan Cruzan, 301-827-6242 Consumer Inquiries: 888-INFO-FDA...
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Neuroscience
Reminyl (galantamine hydrobromide)
From the New York Times:
Johnson & Johnson Reports Reminyl Deaths
By THE ASSOCIATED PRESS
Published: January 21, 2005
Filed at 5:08 p.m. ET
RARITAN, N.J. (AP) -- Patients taking Alzheimer's drug Reminyl in a test for another use had higher death rates than those taking a placebo, Johnson & Johnson Pharmaceutical Research & Development LLC announced Friday.
The patients had mild cognitive impairment, and the J&J company is no longer pursuing Reminyl as a treatment for the condition and has not submitted any applications for such use, spokeswoman Carol Goodrich said.
Reminyl was approved in 2001 as a treatment for mild to moderate Alzheimer's disease. The higher death rate was not observed in Alzheimer's trials, Goodrich said.
[ ... Read the full article ...] (free registration required)
- Alzheimer's Disease: Gammagard Fails
From the company press release: Baxter Announces Topline Results of Phase III Study of Immunoglobulin for Alzheimer's Disease DEERFIELD, Ill., May 7, 2013 - Baxter International Inc. (NYSE:BAX) today announced that its Phase III clinical study of...
- Clinical Trials: Solanezumab In Alzheimer's Disease
From Bloomberg: Eli Lilly Shares Rise on Alzheimer’s Drug Hopes By Drew Armstrong and Robert Langreth Dec 6, 2011 [snip] "Solanezumab is an antibody designed to clear protein fragments called beta amyloid that clutter the brains of patients with Alzheimer’s...
- Fda: Alzheimer Disease, Aricept (donepezil Hydrochloride)
From the FDA last week: FDA Approves Expanded Use of Treatment for Patients With Severe Alzheimer's Disease FOR IMMEDIATE RELEASE P06-168 October 13, 2006 Media Inquiries: Susan Cruzan, 301-827-6242 Consumer Inquiries: 888-INFO-FDA...
- Abstract Of The Day: Alzheimer Disease Drug Treatments
Birks J. Cholinesterase inhibitors for Alzheimer's disease. Cochrane Database Syst Rev. 2006 Jan 25; (1): CD005593. BACKGROUND: Since the introduction of the first cholinesterase inhibitor (ChEI) in 1997, most clinicians and probably most patients...
- Business World: Australia's Cogstate
An article from the Australian website, The Age: CogState promotes brain tests to draw takeover offers By Rebecca Urban September 22, 2004 Frustrated by its diminishing value on the Australian sharemarket, diagnostic maker CogState is pitching...