Neuroscience
A news release from the NIH:
Investment in Parkinson's Disease Data Bank Yields Potential Therapy
12th October, 2009
[snip]
Individuals with Parkinson's disease who have higher levels of a metabolite called urate in their blood and in cerebrospinal fluid (CSF) have a slower rate of disease progression, according to a study funded by the National Institutes of Health. A clinical trial is under way to examine the safety and potential benefits of supplemental urate elevation for recently diagnosed Parkinson's patients who have low urate levels.
Investigators demonstrated the link with urate by mining a repository of clinical data and tissue samples collected from Parkinson's patients more than 20 years ago as part of a pioneering study called DATATOP, funded by NIH's National Institute of Neurological Disorders and Stroke (NINDS). The new study appears in Archives of Neurology. It was funded primarily by NINDS, with additional support from the Department of Defense and private organizations.
"This study speaks to the value of saving data and biospecimens from large clinical studies, and making them available to the research community to pursue new, unanticipated ideas," said Michael Schwarzschild, M.D., Ph.D., an associate professor of neurology at Massachusetts General Hospital in Boston, who lead the study together with Alberto Ascherio, M.D., Dr.PH, a professor of epidemiology and nutrition at the Harvard School of Public Health.
[snip]
- Parkinson's Disease: Narrative From A Spouse
From The Times (UK): Case study: ‘It’s hard to recognise the man I married’ Judith Magill’s retirement dreams were dashed when her husband, Patrick, had Parkinson's disease diagnosed aged 57 21 September 2009 [snip] "People die with Parkinson’s...
- Rasagiline And Parkinson's Disease
From the FDA on the 17th of May: FDA Approves New Treatment for Parkinson's Disease The Food and Drug Administration today approved Azilect (rasagiline), a new molecular entity, for the treatment of Parkinson's disease. The drug is a monoamine...
- Parkinson Disease, Creatine, And Minocycline
From an NIH new release: Preliminary Study Shows Creatine and Minocycline May Warrant Further Study In Parkinson’s Disease A National Institutes of Health-sponsored clinical trial with 200 Parkinson's disease patients has shown...
- Upcoming Event: Washington, D.c., 20 October 2005
A press release from the NIH: Tuesday, October 11, 2005 CONTACT: Margo Warren 301-496-5751 Science Reporters Briefing: New Advances in Parkinson’s Research and Treatment What: The National Institute of Neurological Disorders...
- In The Weeklies
This week's issue of the New England Journal of Medicine (09 December 2004) includes two research papers and one editorial comment on topics concerning Parkinson disease: Levodopa and the Progression of Parkinson's Disease by The Parkinson...
Neuroscience
Parkinson's Disease: DATATOP
A news release from the NIH:
Investment in Parkinson's Disease Data Bank Yields Potential Therapy
12th October, 2009
[snip]
Individuals with Parkinson's disease who have higher levels of a metabolite called urate in their blood and in cerebrospinal fluid (CSF) have a slower rate of disease progression, according to a study funded by the National Institutes of Health. A clinical trial is under way to examine the safety and potential benefits of supplemental urate elevation for recently diagnosed Parkinson's patients who have low urate levels.
Investigators demonstrated the link with urate by mining a repository of clinical data and tissue samples collected from Parkinson's patients more than 20 years ago as part of a pioneering study called DATATOP, funded by NIH's National Institute of Neurological Disorders and Stroke (NINDS). The new study appears in Archives of Neurology. It was funded primarily by NINDS, with additional support from the Department of Defense and private organizations.
"This study speaks to the value of saving data and biospecimens from large clinical studies, and making them available to the research community to pursue new, unanticipated ideas," said Michael Schwarzschild, M.D., Ph.D., an associate professor of neurology at Massachusetts General Hospital in Boston, who lead the study together with Alberto Ascherio, M.D., Dr.PH, a professor of epidemiology and nutrition at the Harvard School of Public Health.
[snip]
- Parkinson's Disease: Narrative From A Spouse
From The Times (UK): Case study: ‘It’s hard to recognise the man I married’ Judith Magill’s retirement dreams were dashed when her husband, Patrick, had Parkinson's disease diagnosed aged 57 21 September 2009 [snip] "People die with Parkinson’s...
- Rasagiline And Parkinson's Disease
From the FDA on the 17th of May: FDA Approves New Treatment for Parkinson's Disease The Food and Drug Administration today approved Azilect (rasagiline), a new molecular entity, for the treatment of Parkinson's disease. The drug is a monoamine...
- Parkinson Disease, Creatine, And Minocycline
From an NIH new release: Preliminary Study Shows Creatine and Minocycline May Warrant Further Study In Parkinson’s Disease A National Institutes of Health-sponsored clinical trial with 200 Parkinson's disease patients has shown...
- Upcoming Event: Washington, D.c., 20 October 2005
A press release from the NIH: Tuesday, October 11, 2005 CONTACT: Margo Warren 301-496-5751 Science Reporters Briefing: New Advances in Parkinson’s Research and Treatment What: The National Institute of Neurological Disorders...
- In The Weeklies
This week's issue of the New England Journal of Medicine (09 December 2004) includes two research papers and one editorial comment on topics concerning Parkinson disease: Levodopa and the Progression of Parkinson's Disease by The Parkinson...