Neuroscience
After a long hiatus, Dan Dright is posting again at N E U R O N E R D and has this to say about dopamine (and a new article in Science about impulsive rats):
- Abc News Says: 'trust Drug' Oxytocin Unbelievable For Now
BUT 'Adventure Center' Explains Why Brain Craves New Sensations Newness Factor Weighs in on Brain By ALLYSON T. COLLINS ABC News Medical UnitJune 25, 2008—...Humans may be wired to seek out new experiences, according to a study published Wednesday...
- D1 Receptor Knock-out Mice Say, "no Cocaine For Us!"
"However, we'll still take plenty of food and opioid agonists!" Unlike mice with the dopamine D2 receptor "knocked out," D1 receptor-deficient mice will no longer self-administer cocaine: Caine SB, Thomsen M, Gabriel KI, Berkowitz JS, Gold LH, Koob...
- Neuropsychology Abstract Of The Day: Cognitive Correlates Of Impulsive Behavior In Mlld Alzheimer's Disease
A multidimensional approach to impulsivity changes in mild Alzheimer's disease and control participants: Cognitive correlates Cortex. 2011 Sep 2; Rochat L, Billieux J, Juillerat Van der Linden AC, Annoni JM, Zekry D, Gold G, Van der Linden M Abstract...
- Abstract Of The Day: Of Time And The River
Takahashi T. Time-estimation error following Weber-Fechner law may explain subadditive time-discounting.. Medical Hypotheses. 2006 Jul 25; [Epub ahead of print] Department of Cognitive and Behavioral Science, The University of Tokyo, 3-8-1 Komaba, Meguro,...
- Parkinson Disease
From an NIH press release on 04 July 2006: Dopamine Drug Leads to New Neurons and Recovery of Function in Rat Model of Parkinson's Disease In preliminary results, researchers have shown that a drug which mimics the effects of...
Neuroscience
Dope-a-mine!
After a long hiatus, Dan Dright is posting again at N E U R O N E R D and has this to say about dopamine (and a new article in Science about impulsive rats):
That's why they call it Dope-a-mine
Once again the chicken/egg argument is revisited vis-a-vis addiction. Do drugs make us impulsive or does impulsivity make us do drugs?
A new article in Science shows evidence that a paucity of functional D2/3 receptors in the ventral striatum "high-impulsivity" rats is correlated to a higher tendency to self-administer cocaine when given access to drug.
The implications are positive, in that it is always good to see work that supports a non-moral-depravity line of reasoning behind addiction; on the other hand, some reports in the more mainstream news take a harder nature/nurture line with headers like "Study: Addicts born, not made." and that sort of thing. I always worry about backlash from social scientists whenever I see stuff like that.
- Abc News Says: 'trust Drug' Oxytocin Unbelievable For Now
BUT 'Adventure Center' Explains Why Brain Craves New Sensations Newness Factor Weighs in on Brain By ALLYSON T. COLLINS ABC News Medical UnitJune 25, 2008—...Humans may be wired to seek out new experiences, according to a study published Wednesday...
- D1 Receptor Knock-out Mice Say, "no Cocaine For Us!"
"However, we'll still take plenty of food and opioid agonists!" Unlike mice with the dopamine D2 receptor "knocked out," D1 receptor-deficient mice will no longer self-administer cocaine: Caine SB, Thomsen M, Gabriel KI, Berkowitz JS, Gold LH, Koob...
- Neuropsychology Abstract Of The Day: Cognitive Correlates Of Impulsive Behavior In Mlld Alzheimer's Disease
A multidimensional approach to impulsivity changes in mild Alzheimer's disease and control participants: Cognitive correlates Cortex. 2011 Sep 2; Rochat L, Billieux J, Juillerat Van der Linden AC, Annoni JM, Zekry D, Gold G, Van der Linden M Abstract...
- Abstract Of The Day: Of Time And The River
Takahashi T. Time-estimation error following Weber-Fechner law may explain subadditive time-discounting.. Medical Hypotheses. 2006 Jul 25; [Epub ahead of print] Department of Cognitive and Behavioral Science, The University of Tokyo, 3-8-1 Komaba, Meguro,...
- Parkinson Disease
From an NIH press release on 04 July 2006: Dopamine Drug Leads to New Neurons and Recovery of Function in Rat Model of Parkinson's Disease In preliminary results, researchers have shown that a drug which mimics the effects of...